Earlier this year, the Ivy Brain Tumor Center received FDA approval for a Phase 0 clinical trial to study a first-in-human drug-device combination that uses MRI-guided focused ultrasound in combination with aminolevulinic acid to selectively target and kill tumor cells. Peter Hofland of Onco'Zine covers the story in this article and what it could mean for the brain tumor community.
SonALAsense Pioneers Sonodynamic Therapy, a First-in-Class Noninvasive Therapy for Lethal Brain Cancers; Enters Into a Collaboration and License Agreement With Insightec and a Collaboration Agreement with Ivy Brain Tumor Center to Conduct the First-in-Man Clinical Trial for Recurrent Glioblastoma
The Ivy Brain Tumor Center is excited to collaborate with SonALAsense to conduct this first-in-human clinical trial that will rapidly assess a noninvasive drug-device combination therapy in patients with glioblastoma. This marks a major step forward for brain cancer patients as this novel approach has the potential to change the lives of hundreds of thousands of people impacted by this disease.
Ivy Brain Tumor Center Initiates Phase 0 Clinical Trial with BeiGene for Newly Diagnosed and Recurrent Glioblastoma
The Ivy Brain Tumor Center is conducting the first-ever Phase 0 clinical trial for newly diagnosed glioblastoma patients. This study will evaluate BeiGene’s pamiparib in combination with fractionated radiotherapy and will also be available to patients with recurrent glioblastoma.
In the eleventh annual edition of the International Brain Tumour Alliance (IBTA) magazine, Dr. Nader Sanai explains how the Ivy Brain Tumor Center's unique Phase 0 clinical trials program is providing tailored care for individuals struggling with brain cancer.
Navigating a brain tumor diagnosis can be overwhelming. That's where Jacki Garcia comes in. Jacki is a nurse navigator for Barrow patients with brain tumors, including those who undergo Phase 0 clinical trials at the Ivy Brain Tumor Center.
Zaman Mirzadeh, MD, PhD, an assistant professor and neurosurgeon-scientist at the Ivy Brain Tumor Center and Barrow Neurological Institute, has been named a recipient of the National Institutes of Health (NIH) Director’s New Innovator Award.
The Ivy Brain Tumor Center at Barrow Neurological Institute is pleased to announce the addition of Wonsuk Yoo, PhD, as associate professor of biostatistics. Dr. Yoo’s expertise in preclinical and clinical trial design will be critical in evaluating new treatment modalities for brain tumor patients.
The Ivy Center has appointed Shwetal Mehta, Ph.D., as its chief operating officer. Dr. Mehta is a nationally recognized molecular neuro-oncologist who has distinguished herself as a rising star in brain tumor biology.
Ivy Brain Tumor Center and Vivace Therapeutics Collaborate to Test Targeted Agent in Glioblastoma and Meningioma
Ivy Brain Tumor Center has announced a new partnership with Vivace Therapeutics. This collaboration will allow researchers at the Ivy Center to evaluate a first-in-class TEAD inhibitor in glioblastoma and meningioma.
Ivy Brain Tumor Center and BridgeBio Pharma’s QED Therapeutics announce dosing of first patient in investigator-initiated Phase 0/2 clinical trial of infigratinib in recurrent glioblastoma
The Ivy Brain Tumor Center announced that the first patient has been dosed in an investigator-initiated Phase 0/2 clinical trial of infigratinib in recurrent high-grade glioma driven by FGFR genetic alterations. Infigratinib is an investigational, orally administered, FGFR1-3 selective tyrosine kinase inhibitor being developed by BridgeBio Pharma, Inc. (Nasdaq: BBIO) affiliate company QED Therapeutics, Inc.