Discovering Hope Every Day

The Largest Phase 0 Clinical Trials Program in the World

The Ivy Brain Tumor Center is a nonprofit translational research program that offers state-of-the-art clinical trials for patients with even the most aggressive brain tumors.

Brain Tumor Treatment at Ivy

The Ivy Brain Tumor Center is a leader in brain tumor research and treatment. The Ivy Center is located in Phoenix, Arizona, at Barrow Neurological Institute, the highest-volume operative brain tumor center in the U.S.

Whether benign or malignant, a brain tumor can be life-changing. The Ivy Center’s multidisciplinary team of healthcare professionals and scientists work to understand the molecular structure of each patient’s brain tumor to determine its pathology and the most effective treatment plan. Explore a variety of brain tumor types we treat.

Tumors we treat

Primary Brain Tumor Types

As one of the world’s largest brain tumor treatment centers, the Ivy Center utilizes advanced therapies, state-of-the-art technology and innovative clinical trials to tailor each patient’s treatment plan to their individualized needs and circumstances. No two brain tumors are alike and each tumor requires a treatment regimen designed for its unique genetic composition.

While each patient’s brain tumor experience is different, those on the receiving end of the diagnosis share the overwhelming feelings of worry, fear and stress. No one should have to cope with a brain cancer diagnosis alone. We understand the uncertainty of your circumstances. Our team is here for you every step of the way.

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Ian Youngblood

“At the Ivy Brain Tumor Center, you have people that take the time to study and research and they are committed to finding a cure for patients. It's a comfort to know that this institution is right here in my backyard.”

Ian Youngblood Brain Tumor Survivor

Jenn Ortiz

“When given an opportunity to participate in a clinical trial at the Ivy Brain Tumor Center – take it! Experimental clinical trials provide information that will eventually lead to a cure, and most importantly, they give HOPE!”

Jenn Ortiz Living with Glioblastoma since 2020

Ivy Brain Tumor Center

“The progress achieved by the Ivy Center’s Phase 0 clinical trials program has surpassed anything I have seen in the 16 years I have been funding brain cancer research. The new building in Phoenix will serve to leverage this success, so the Center can move even faster to discover and develop a new FDA-approved therapy for brain cancer.”

Catherine Ivy President and Founder, Ben & Catherine Ivy Foundation

Clinical Trials

Ivy Brain Tumor Center clinical trials play a pivotal role in developing new therapies and advancing treatment options that make a significant impact on patient outcomes. The Ivy Center operates the world’s largest Phase 0 clinical trials program in the world. 

Latest from Ivy

Ivy Brain Tumor Center announces Phase 0/2 clinical readout of niraparib indicating significant improvement in overall survival of newly diagnosed glioblastoma patients

The Ivy Brain Tumor Center has released promising Phase 0/2 clinical trial results for niraparib, showing a significant improvement in overall survival for newly diagnosed glioblastoma patients, with survival times nearly doubling to 20.3 months compared to standard care. These findings will be presented at the 2024 ASCO Annual Meeting. Encouraged by these results, GSK is supporting the initiation of a global Phase 3 trial to further evaluate niraparib versus standard care.

No Victory Too Small in Brain Tumor Treatment 

Discover Zach Fyke’s inspiring journey through brain tumor treatment in our latest blog post, “No Victory Too Small in Brain Tumor Treatment.” From a life-altering diagnosis to celebrating milestones with the Victory Bell at the Ivy Brain Tumor Center, Zach’s story highlights the importance of acknowledging every achievement, no matter how small. Read the full story to see how every small victory counts.

Brain Tumor Talk Ep. 1: Brain Tumor Basics with Guest Dr. Nader Sanai

Discover the complexities of brain tumors in the debut episode of Brain Tumor Talk with Dr. Nader Sanai from the Ivy Brain Tumor Center at Barrow Neurological Institute. Explore types, symptoms, and cutting-edge treatments for one of the most challenging cancers. Essential listening for patients, caregivers, and healthcare enthusiasts.

Ivy Brain Tumor Center Announces Promising Results of Phase 0/1 Glioblastoma Study at the American Association for Cancer Research Annual Meeting

The Ivy Brain Tumor Center announced initial results from a Phase 0/1b clinical trial of AZD1390, in combination with radiation therapy, in newly diagnosed, MGMT-unmethylated glioblastoma. Results from this study will be presented at the American Association for Cancer Research Annual Meeting and demonstrate that AZD1390 may be a potent radiosensitizer in both newly diagnosed and recurrent glioblastoma patients. Read the press release to learn more.

A Mental Mindset for Brain Cancer

Jeff Staudt shares his compelling journey after being diagnosed with glioblastoma, an aggressive brain tumor. Facing a severe prognosis, Jeff chose positivity and determination over surrender, a decision that has defined his eight-year battle with cancer. Highlighting the critical role of mindset, Jeff’s story illustrates how a strong mindset, alongside a tailored medical treatment plan, can defy the odds. Read his full story!