Discovering Hope.
Every Day.

The Largest Phase 0 Clinical Trials Program in the World
The Ivy Brain Tumor Center is a nonprofit translational research program that offers state-of-the-art clinical trials for patients with even the most aggressive brain tumors.
Clinical Trial
Noninvasive Sonodynamic Therapy
The Ivy Center has treated its first patient in a clinical trial of a noninvasive drug-device combination therapy for recurrent glioblastoma developed by SonALAsense in collaboration with INSIGHTEC.
Individualized Treatment in a Fraction of the Time
When a brain tumor patient is referred to an Ivy Phase 0 clinical trial, we partner with their physicians and treatment team on a path forward.
Programs in Place for Rapid Clinical Testing
Partner with the nation's largest operative brain tumor program that's employing a bold, early-phase clinical trials strategy to rapidly identify new effective therapies.

Phase 0 Trials

Ivy Phase 0 clinical trials allow patients to receive individualized treatment in a fraction of the time and costs associated with traditional drug research and development.

Benefits of an Ivy Phase 0 Trial

Saves Valuable Time

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Drug effects on a patient’s tumor are directly measured within 10 days of surgery. If an experimental regimen is ineffective, the patient can transition to another type of therapy without losing time or options.

Personalizes Treatment

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Genetic testing with unprecedented depth allows us to match tumors to new combination drug regimens. Due to the speed in which our trials open and close, we are able to test more new therapies than any other clinical trials program. 

Tests New Drugs

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Every Ivy Center drug combination tests new mechanisms never before trialed in brain tumor patients.  As a nonprofit organization, there is no conflict of interest or hidden agenda in selecting which drugs to include in our program.

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Nick: Patient Survivor

The day after his graduation from San Diego State University, Nick was diagnosed with a recurrence of his malignant meningioma. Nick knew he wasn’t going to have a lot of options, but we had just opened a Phase 0 clinical trial for this exact indication.

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In honor of Brain Tumor Awareness Month, Cindy Westphal, wife of basketball Hall of Famer, Paul Westphal, recalls her husband’s journey with glioblastoma and asks for your support of the Ivy Brain Tumor Center’s mission to contribute to a cure for brain cancer within this decade.

World-renowned neurosurgeon, Dr. Robert F. Spetzler, recalls his sister-in-law’s diagnosis with glioblastoma and the personal connections that guided him through his career.

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Am I Eligible?

Submit a Trial Screening Request today and an Ivy Navigator will contact you within 48 hours to complete the initial patient assessment.

Determine your Eligibility