Recurrent High-Grade Glioma

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Brain tumor patient gazing up with hope
Temsirolimus in Recurrent High-Grade Glioma
  • January 17, 2023
A Phase 0 dose-escalation study using superselective intra-arterial cerebral infusion of temsirolimus for the treatment of recurrent high-grade glioma. 
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Magnetic resonance imaging (MRI) of the brain, brain tumor
AZD1390 FOR RECURRENT GLIOBLASTOMA
  • March 15, 2022
A Phase 0/1b clinical trial to evaluate AZD1390 in patients with recurrent glioblastoma.
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Rendering of patient receiving MRI treatment
SONODYNAMIC THERAPY IN RECURRENT HIGH-GRADE GLIOMA
  • March 5, 2022
A Phase 0 research study of intravenous Aminolevulinic Acid Hydrochloride (ALA) and MR-guided focused ultrasound device (MRgFUS) in recurrent high-grade glioma patients
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Magnetic resonance imaging (MRI) of the brain, brain tumor
INFIGRATINIB FOR RECURRENT HIGH-GRADE GLIOMA
  • February 4, 2021
A Phase 0 study of infigratinib in recurrent high-grade glioma patients with an FGFR gene fusion scheduled for resection to evaluate central nervous system (CNS) penetration with PK triggered expansion cohort
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RIBOCICLIB PLUS EVEROLIMUS FOR RECURRENT HIGH-GRADE GLIOMA
  • February 1, 2021
A Phase 0/2 study of ribociclib in combination with everolimus in preoperative Rb-intact recurrent high-grade glioma patients scheduled for resection
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