Temsirolimus in Recurrent High-Grade Glioma
  • January 17, 2023
A Phase 0 dose-escalation study using superselective intra-arterial cerebral infusion of temsirolimus for the treatment of recurrent high-grade glioma. 
Learn More
AZD1390 FOR RECURRENT GLIOBLASTOMA
  • March 15, 2022
A Phase 0/1b clinical trial to evaluate AZD1390 in patients with recurrent glioblastoma.
Learn More
SONODYNAMIC THERAPY IN RECURRENT HIGH-GRADE GLIOMA
  • March 5, 2022
A Phase 0 research study of intravenous Aminolevulinic Acid Hydrochloride (ALA) and MR-guided focused ultrasound device (MRgFUS) in recurrent high-grade glioma patients.
Learn More
PAMIPARIB IN NEWLY DIAGNOSED AND RECURRENT GLIOBLASTOMA
  • February 28, 2022
A Phase 0/2 study of pamiparib (a PARP inhibitor) in newly diagnosed and recurrent glioblastoma patients to evaluate brain penetration and tumor effects.
Learn More
DSC-MRI FOR RECURRENT GLIOBLASTOMA
  • February 5, 2021
A Phase 2 trial that studies how well dynamic susceptibility contrast-enhanced magnetic resonance imaging (DSC-MRI) works in measuring relative cerebral blood volume (rCBV) for early response to Bevacizumab in patients with glioblastoma that has come back. DSC-MRI may help evaluate changes in the blood vessels within the cancer to determine a patient's response to treatment.
Learn More
RIBOCICLIB FOR RECURRENT GLIOBLASTOMA
  • February 3, 2021
A Phase 0/2 study of ribociclib in preoperative Rb-positive recurrent high-grade glioma patients scheduled for resection.
RIBOCICLIB PLUS EVEROLIMUS FOR RECURRENT HIGH-GRADE GLIOMA
  • February 1, 2021
A Phase 0/2 study of ribociclib in combination with everolimus in preoperative Rb-intact recurrent high-grade glioma patients scheduled for resection.
Learn More